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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
16.06
Human Site:
T182
Identified Species:
25.24
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
T182
F
S
V
N
L
F
R
T
L
P
P
S
S
N
P
Chimpanzee
Pan troglodytes
XP_518483
668
77639
T248
F
S
V
N
L
F
R
T
L
P
P
S
S
N
P
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
F172
S
N
P
T
G
A
E
F
D
P
E
E
D
E
P
Dog
Lupus familis
XP_538927
602
69962
T182
F
S
V
N
L
F
R
T
L
P
P
S
S
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
P148
F
L
R
F
L
E
S
P
D
F
Q
P
N
I
A
Rat
Rattus norvegicus
XP_001062510
563
65413
L173
A
A
W
P
H
L
Q
L
V
Y
E
F
F
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
S78
F
F
L
R
F
L
E
S
P
D
F
Q
P
N
V
Chicken
Gallus gallus
XP_419321
459
53699
F83
P
H
E
R
E
E
L
F
I
Q
K
L
R
Q
C
Frog
Xenopus laevis
NP_001087638
506
58853
V130
R
A
A
L
S
E
M
V
E
Y
I
T
H
N
R
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
S174
F
R
T
L
P
P
S
S
N
P
T
G
A
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
T263
F
A
V
N
L
F
R
T
L
P
P
S
S
N
P
Honey Bee
Apis mellifera
XP_392477
724
84384
G172
P
P
S
S
N
P
N
G
A
E
F
D
P
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
P171
P
H
G
A
E
F
D
P
E
E
D
E
P
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
I134
K
N
I
K
E
K
D
I
K
R
Q
T
L
L
E
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
P355
F
K
I
N
L
F
R
P
I
P
P
P
V
N
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
13.3
100
N.A.
13.3
0
N.A.
13.3
0
6.6
13.3
N.A.
93.3
0
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
20
20
N.A.
26.6
6.6
20
26.6
N.A.
100
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
7
7
0
7
0
0
7
0
0
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
14
0
14
7
7
7
7
0
0
% D
% Glu:
0
0
7
0
20
20
14
0
14
14
14
14
0
20
14
% E
% Phe:
54
7
0
7
7
40
0
14
0
7
14
7
7
0
7
% F
% Gly:
0
0
7
0
7
0
0
7
0
0
0
7
0
0
0
% G
% His:
0
14
0
0
7
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
14
0
0
0
0
7
14
0
7
0
0
7
0
% I
% Lys:
7
7
0
7
0
7
0
0
7
0
7
0
0
0
0
% K
% Leu:
0
7
7
14
40
14
7
7
27
0
0
7
7
14
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
14
0
34
7
0
7
0
7
0
0
0
7
47
0
% N
% Pro:
20
7
7
7
7
14
0
20
7
47
34
14
20
0
40
% P
% Gln:
0
0
0
0
0
0
7
0
0
7
14
7
0
7
0
% Q
% Arg:
7
7
7
14
0
0
34
0
0
7
0
0
7
0
14
% R
% Ser:
7
20
7
7
7
0
14
14
0
0
0
27
27
0
0
% S
% Thr:
0
0
7
7
0
0
0
27
0
0
7
14
0
7
0
% T
% Val:
0
0
27
0
0
0
0
7
7
0
0
0
7
0
7
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _